St. Mary's Winter 2021/2022 Schedule
| Date | Time | Opponent | Score | Location |
| December | ||||
| Sat, 12/4/21 | 7:00 pm | Paradise Honors | W 63 - 61 | Paradise Honors |
| Wed, 12/8/21 | 7:30 pm | Brophy | L 62 - 65 | Chaparral - Hoophall West |
| Sat, 12/11/21 | 5:30 pm | Bishop Gorman | L 63 - 90 | Footprint Arena - Hoophall West |
| Thu, 12/16/21 | 7:00 pm | Rock Canyon | W 68 - 61 | St. Mary's |
| Tue, 12/21/21 | 6:15 pm | Thunderbird | W 77 - 33 | Footprint Arena |
| Mon, 12/27/21 | 5:20 pm | Clayton Valley Charter | Torrey Pines Holiday Classic | |
| Tue, 12/28/21 | —:— — | TBD | Torrey Pines Holiday Classic | |
| Wed, 12/29/21 | —:— — | TBD | Torrey Pines Holiday Classic | |
| Thu, 12/30/21 | —:— — | TBD | Torrey Pines Holiday Classic | |
| January | ||||
| Sat, 1/1/22 | 8:00 pm | Peoria | Footprint Arena | |
| Tue, 1/4/22 | 7:00 pm | Poston Butte | St. Mary's | |
| Thu, 1/6/22 | —:— — | TBD | Allstate Sugar Bowl, New Orleans | |
| Fri, 1/7/22 | —:— — | TBD | Allstate Sugar Bowl, New Orleans | |
| Sat, 1/8/22 | —:— — | TBD | Allstate Sugar Bowl, New Orleans | |
| Tue, 1/11/22 | 7:00 pm | Shadow Mountain | Shadow Mountain | |
| Fri, 1/14/22 | 7:00 pm | Tempe | Tempe | |
| Tue, 1/18/22 | 7:00 pm | Thunderbird | St. Mary's | |
| Fri, 1/21/22 | 7:00 pm | Moon Valley | St. Mary's | |
| Tue, 1/25/22 | 7:00 pm | Greenway | St. Mary's | |
| Thu, 1/27/22 | 7:00 pm | Shadow Mountain | St. Mary's | |
| Sat, 1/29/22 | 6:00 pm | Milton | Milton, GA | |
| February | ||||
| Tue, 2/1/22 | 7:00 pm | Tempe | St. Mary's | |
| Wed, 2/2/22 | 7:00 pm | Seton | St. Mary's | |
| Thu, 2/3/22 | 7:00 pm | Greenway | Greenway | |
| Tue, 2/8/22 | 7:00 pm | Moon Valley | Moon Valley | |
